Publications

  • Coleman, M.D. Ha, S-D, Haeryfar, S.M.M., Barr, S.D., Kim, S.O.*: Cathepsin B plays a key role in optimal production of the influenza A virus. J. of Virology and Antiviral Research (2017, December) Issue 4, Volume 6 (accepted)
  • Ha S-D., Cho W., Kim S.O.*: Resistance to cell cycle arrest induced by Anthrax lethal toxin is reversed by HDAC8-PTEN-PI3K-AKT signaling axis. Toxins 2017, 9(5), 162; doi:10.3390/toxins9050162.
  • KOSCIK R, REID R, KIM S.O., LI W., CHALLIS J.R.G.3, BOCKING A.D.: Effect of Lactobacillus rhamnosus GR-1 supernatant on cytokine and chemokine output from human amnion cells treated with lipoteichoic acid and lipopolysaccharide. Reproductive Science (accepted)
  • Ha S-D., Meshkibaf S., Reid C., Kim S.O.*: Inhibition of IL-1β expression by anthrax lethal toxin is reversed by HDAC8 inhibition in murine macrophages. J Biol Chem (2016, Feb). PMID: 26912657.
  • Meshkibaf S., Martin A., Kim S.O.*: Protective role of G-CSF in dextran sulfate sodium-induced acute colitis through generating gut-homing immune regulatory macrophages. Cytokine 2016 Feb 78:69-78. PMID: 26687628
  • Meshkibaf S., Fritz J., Gottschalk M., Kim S.O.: Preferential production of G-CSF by a protein-like Lactobacillus rhamnosus GR-1 secretory factor through activating TLR2-dependent signaling events without activation of JNKs. BMC Microbiol. 2015 Oct 26;15(1):238. PMID: 26502905.

  • Yang S., Reid G., Challis J.R.G., Kim S.O., Gloor G.B., Bocking A.D.: Is there a role for probiotics in the prevention of preterm birth? Frontiers in Immunology: Review 6:62. doi: 10.3389/fimmu.2015.00062. eCollection (2015). PMID: 25741339

  • HDAC8-mediated epigenetic reprogramming plays a key role in resistance to anthrax lethal toxin-induced pyroptosis in macrophages. Journal of Immunology 193(3):1333-43 (2014) PMID: 24973453.

  • Meshkibaf S., Gower M., Dekaban G., Kim S.O.*: G-CSF preferentially supports the generation of gut-homing Gr-1high macrophages in M-CSF-treated bone marrow cells. Journal of Leukocyte Biology 96(4):549-61 (2014). PMID: 24981628.

  • Yang S., Li W., Challis J., Reid G., Kim S.O., Bocking A. . Probiotic Lactobacillus rhamnosus GR-1 supernatant prevents lipopolysaccharide-induced preterm birth and reduces inflammation in pregnant CD-1 mice. American Journal of Obstetrics & Gynecology 211(1):44e1-44e12 (2014). PMID: 24486224.

  • Li W., Yang S., Kim SO., Reid G., Challis JR., Bocking AD: Lipopolysaccharide-Induced Profiles of Cytokine, Chemokine, and Growth Factors Produced by Human Decidual Cells Are Altered by Lactobacillus rhamnosus GR-1 Supernatant. Reproductive Sci. 21(7):939-947 (2014). PMID:24429676.

  • Park S., Ha SD., Coleman M., Meshkibaf S., Kim S.O.*: p62/SQSTM1 enhances NOD2-mediated signaling and cytokine production through stabilizing NOD2 oligomers. PLoS ONE 8(2): e57138 (2013).

  • Ha SD., Park S., Han CY., Nguyen ML., Kim S.O.*: Cellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and ROS generation through down-regulating MLN64 in macrophages. Mol. Cell. Biol. (2012). PMID: 23028046

  • Ha S-D., Park S.W., Hattlmann C., Barr S.D., Kim S.O.*: Inhibition or deficiency of cathepsin B leads defects in HIV-1 Gag pseudoparticle release in macrophages and HEK293T cells. Antiviral Res 93(1): 175-184 (2012). PMID: 22138708

  • Lee S., Wang Y., Kim S.O., Han J.: AMPD3 is involved in anthrax LeTx-induced macrophage cell death. Protein Cell 2(7):564-572 (2011). PMID: 21822801

  • Martins A., Spanton S., Sheikh H.I., Kim S.O.*: The anti-inflammatory role of granulocyte-colony stimulating factor in macrophage-dendritic cell crosstalk after Lactobacillus rhamnosus GR-1-exposure. Journal of Leukocyte Biology 89(6):907-915 (2011). PMID: 21385950.

  • Ha S-D., Ham B., Morgridge J., Saftig P., Lin S., Kim S.O.: Cathepsin B-mediated autophagy flux facilitates the anthrax toxin receptor 2-mediated delivery of anthrax lethal factor into the cytoplasm. J Biol Chem 285(3):2120-9 (2010). PMID: 19858192.

  • Ono K., Wang X., Kim SO., Armstrong LC., Bornstein P., Han J.: Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing. Protein Cell 1(2): 161-173 (2010). PMID: 21088703.

  • Martins A., Colqhoun P., Reid G., Kim S.O.*: Reduced expression of basal and probiotic-inducible G-CSF in intestinal mononuclear cells is associated with inflammatory bowel disease. Inflammatory Bowel Diseases 15(4):515-25 (2009). PMID: 19058228. *corresponding author. Selected as recommended reading for Faculty of 1000 Biology (http://www.f1000biology.com/article/id/1139083).
  • Yeganegi M., Watson C.S., Martins A., Kim S.O., Reid G., Challis J.R.G., Bocking A.D.: Effect of Lactobacilli Supernatant and Fetal Sex on LPS-Induced Cytokines and Prostaglandin-Regulating Enzymes in Human Placental Trophoblasts: Implications for Treatment of Bacterial Vaginosis and Prevention of Preterm Labour. Amercian Journal of Obstetrics and Gynecology 200(5):532.e1-8 (2009). PMID: 19285652. Co-author: contributed in concept and experimental approach development of the study, provided reagents and input in writing manuscript.
  • Ha S-D., Martins A., Khazaie K., Han J., Kim S.O.*:Cathepsin B is involved in the post-translational processing of tumor necrosis factor-α in lipopolysaccharide-activated macrophages. J. Immunology 181(1):690-697 (2008). PMID: 18566436.
  • Ha S-D.§, Ng D.§, Pelech S., Kim S.O.*: Critical role of PI3-K/AKT/GSK-3β signaling pathway in recovery from anthrax lethal toxin-induced cell cycle arrest and MEK cleavage in human monocytic cell lines. J Biol Chem. 282(50):36230-36239 (2007). PMID: 17951252. §Equal contribution. *Selected as recommended reading for Faculty of 1000 Biology (http://www.f1000biology.com/article/id/1093935).
  • Ha S-D., Ng D., Lamoth J., Valvano M., Han J., Kim, S.O.*: Down-regulation BNIP3 and BNIP3L through inactivation of p38 is the mechanism for the anthrax lethal toxin-induces resistance in macrophages. J. of Biol Chem 282(36):26275-26283 (2007. Sept). PMID: 17623653.
  • Kang Y.J., Kim S.O., Shimada S., Otsuka M., Watts T., Han J. : 4-1BBL signaling in LPS-activated macrophages is required for sustained TNF production. Nature Immunol. 8(6):601-9 (2007). PMID: 17496895.
  • Kim S.O.*, Ha S-D, Lee S., Stanton S., Beutler B., Han J.: Mutagenesis by Retroviral Insertion in Chemical Mutagen-Generated Quasi-Haploid Mammalian Cells. BioTechnique 42 (4):493-501(2007). *corresponding author; S-D Ha is a postdoctoral fellow under my supervision. PMID: 17489237.
  • Song L., Li J., Ye J., Yu G., Ding J., Zhang D., Ouyang W., Dong J., Kim S.O., Huang C.: p85α acts as a novel signal transducer specifically for cell apoptotic response to UV Radiation. Mol. Cell. Biol. 27(7): 2713-2731 (2007). PMID:17242187.
  • Kim S.O.*, Sheikh H.I., Ha S-D., Martins A., Reid G.: G-CSF-mediated inhibition of JNK is a key mechanism for Lactobaci llus rhamnosus-induced anti-inflammatory effects in macrophages. Cell. Microbiol. 8(12):1958-1971 (2006). PMID: 16889627
  • Xu Y., Kim SO., Li Y., Han J.: Autophagy contributes to caspase-independent macrophage cell death. J. Biol. Chem. 281: 19179-19187 (2006). PMID: 16702227.
  • Reid G., Kim SO., Kohler GA.: Selecting, testing and understanding probiotics microorganisms. FEMS Immunol. Med. Microbiol. 46:149-157 (2006). PMID: 16487295.
  • Hoebe K, Janssen EM, Kim SO, Alexopoulou L, Flavell RA, Han J, Beutler B.: Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nature Immunol. 4(12):1223-1229 (2003).
  • Hoebe K., Du P., Georgel P., Tabeta K., Kim S.O., Goode, J., Lin P., Mann, N., Mudd S., Crozt K., Sovath S., Han. J., Beutler B.: Identification of Lps2 as a key transducer of MyD88-independent TIR signaling. Nature 424(6950):743-748 (2003 July). PMID: 12872135
  • Kim S.O., Ono K., Tobias P.S., Han J.: Orphan Nuclear Receptor Nur77 is involved in Caspase independent Macrophage Cell Death. J. Exp. Med. 197(11):1441-1452 (2003 June). PMID: 12782711
  • Kim S.O., Jing Q., Hoebe K., Beutler B., Duesbery N.S., Han J.: Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-α. J. Biol. Chem. 278(9):7413-7421 (2003)
  • Ono K, Kim S.O., Han J.: Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death. Mol. Cell. Biol. 23(2):665-676 (2003)
  • Kim S.O., Ono K., Han J.: Apoptosis by pan-caspase inhibitors in lipopolysaccharide-activated macrophages. Am. J. Physiol. 282: L1095-L1105 (2001).
  • Kim S.O., Han J.: Pan-caspase inhibitor zVAD enhances cell death in RAW246.7 macrophages. J. Endotoxin Res. 7(4): 292-296 (2001).
  • Wang X., Ono K., Kim S.O., Kravchenko V., Lin S-C., Han J.: Metaxin is required for tumor necrosis factor-induced cell death. EMBO reports 2(7): 628-633 (2001).
  • Wong A.S.T., Kim S.O., Leung P.C.K., Auersperg N., Pelech S.L.: Profiling of protein kinases in the neoplastic transformation of human ovarian surface epithelium. Gynecol. Oncol. 82: 305-311 (2001).
  • Sayed M., Kim S.O. , Salh B.J., Issinger O-F.: Stress activation of protein kinase CK2 by direct interaction with p38 MAP kinase. J. Biol. Chem. 275(22): 16569-16573 (2000).
  • Kim S.O., Xu Y., Katz S., Pelech S.L.: Cyclic-GMP dependent- and independent-regulation of MAP kinases by sodium nitroprusside in isolated cardiomycotes. Bichem. Biophy. Acta 17; 1496(2-3): 277-284 (2000).
  • Nakano A., Pain T., Kim S.O., Pelech S., Downey J.M., Cohen M.V., Critz S.: Ischemia preconditioning activates MAPKAPK2 but not JNK in the isolated rabbit heart: indicate for involvement of p38 MAPK. Circ Res. 4; 86(2):144-151 (2000).
  • Xu Y., Kim S.O., Liao D-F., Katz S., Pelech S.L.: Stimulation of 90- and 70-kDa ribosomal protein S6 kinases by arginine vasopressin and lysophosphatidic acid in rat cardiomyocytes.. Biochem. Pharmacol. 59:1163-1171 (2000).
  • Kim S.O., Pain T., Pelech S.L., Cohen M.V., Katz S., Downey J.M..: Activation of heat shock recond 27 kinases and casein kinase-2 in ischemic reconditioned rabbit heart. Biochem Cell Biol. 77(6): 559-567 (1999).
  • Kim S.O., Hasahm M.I., Katz S., Pelech S.L.: Insulin regulated protein kinases during postnatal development of rat heart. J. Cell. Biochem. 71; 318-339 (1998).
  • Kim S.O., Irwin P., Katz S., Pelech S.L.: Mitogenic-activated protein kinase pathways during postnatal development of rat heart. J. Cell. Biochem. 71; 286-301 (1998).
  • Kim S.O., Katz S., Pelech S.L.: Expression of second messenger- and cyclin-dependent protein kinases during postnatal development of rat heart. J. Cell. Biochem. 69: 506-521 (1998).
  • Kim S.O., Sahl B., Pelech S.L., Wong G., Katz S.: Activation of Mapkapk2 by adenosine in rat heart. J. NIH Res. (1997) 9: 54
  • Zhanel G.G., Kim S.O., Davidson R.J., Hoban D.J. Nicolle L.E.: Effect of subinhibitory concentrations (sub-MIC) of ciprofloxacin and gentamicin on the adherence of Pseudomonas aeruginosa to Vero cells, urothelial cells and a mouse urinary infection model. Chemotherapy (1993) 39: 105-111
  • Zhanel G.G., Crampton J, Kim S.O., Nicolle L.E., Davidson R.J., Hoban D.J.: Antimicrobial activity of subinhibitory concentrations of ciprofloxacin against Pseudomonas aeruginosa as determined by the killing curve method and the postantibiotic effect. Chemotherapy (1992) 38: 388-394.